Acute Vascular Injuries during CICC placements

by | Jan 25, 2022 | PICCs, Ports and Huber Needles, VAD Insertion | 0 comments

 

Case report of vascular injuries during CICC Placements. It does not only happen to others! Marie is a young mother of two children. She discovered a small mass by self-breast examination. After doing a mammography, a breast tumor was confirmed. Later, she had a partial mastectomy and an axillary node clearance. She was also prescribed an adjuvant chemotherapy with a port catheter in jugular vein placement. Michele was a junior resident who was a few months away from getting her degree as a Gynecologic Surgeon. She took care of the device’s placement. The introducer was advanced with only a small resistance and Michele discovered a pulsatile red flow. She asked the operating room nurse to call the senior surgeon. His answers were: “It is an infrequent problem but not that important” and “you can remove the devices and compress”. Mary was starting to breath with difficulty when the Anesthesiologist called, diagnosed her with coma (Glasgow 7) and put a tracheal tube. An Angio CT scan was then performed, and a massive stroke attack was confirmed. Mary unfortunately passed away. Michele, the Senior Surgeon, and the Nurse were interviewed by the police.

Photo 1: Case Report

 

Introduction

 

Central venous catheterization (CVC) is a technique commonly used to obtain short and long-term vascular access. There are many potential risks associated with CVC insertion and that can lead to vascular injuries.

Arterial injury or canulation is a complication that can cause potentially fatal complications; hemorrhage, cerebral ischemia, and airway-threatening hematoma formation; and is therefore a particularly feared complication.

 

Vascular injuries exist during CVC placements

 

The North American “closed claims” system, based on practitioners’ declarations to insurance companies, is a good tool for evaluating the existence of complications related to procedures and for the placement of endovascular devices too. In 2004, the inventory of complications included hemothorax, carotid wounds and canulations, and hemomediastinum. Sixty-eight percent of these events resulted in death. From 1970 to 1994, ultrasound was not yet routinely used. However, despite the use of ultrasound from 1995 to 2004, the number of complications related to this type of accident continued to increase. (1,2)

In the UK, over a period of 14 years, 26 claims were found to be related to central venous access. 14 arterial punctures, including three carotid canulations were cited. (3)

In Sweden, an analysis of complaints filed between 2009 and 2017 regarding anesthetic procedures showed that 36 could be linked to a vascular injury. This included four arterial canulations. The risk of arterial injury and occurrence of hematomas and hemothorax appeared to be correlated to the number of attempts. (4) In this series, ultrasound was used in only 20% of cases.

Thomas (2016) studied the reasons for admission to an intensive care unit (ITU) in England and Ireland over a 10-year period. During this time, it was found that 50 out of 1743 admissions were related to complications following central venous access procedures. Thirteen arterial placements were noted (only two were recognized during the procedure). Of these, four had a fluoroscopy exam interpreted as normal. (5)

The study by Lathey et al. (2017) is interesting because it was a prospective multicenter study. It was carried out over a two-week period, with a four-week follow-up, and involved 15 hospitals. All procedures (n = 487) were performed by medical specialists under ultrasound guidance. One hemothorax, one carotid canulation, and five carotid punctures were observed during the period, confirming both the existence and the rarity of these complications. The rate of artery canulation was found to be 0.2%. (6)

Guibert (7) reported the Canadian experience in 2008. After review of the literature and their own case series, a multidisciplinary consensus panel comprised of four vascular surgeons, an anesthesiologist, and an intensivist, was delegated to define the optimal therapeutic strategy to decrease the risk of complications when a large-bore catheter was inadvertently placed in an artery. Management relies on drainage, leaving dilators ⁄catheters in place to reduce bleeding, and urgent repair by surgery or interventional radiology. Thirteen cases of arterial canulation were found in their database and correlated to their 7200 central venous catheter placements resulting in an incidence of 1/1800 or 0.05%.

Returning to the clinical cases of the literature, and comparing the different models of management, they found 47% of complications in the group removed and compressed device versus none in the surgery group.

 

Mechanisms of vascular injuries in CVC placements

 

Bowdle in 2014 explained the mechanism of vascular injuries in CVC placements. (8)

First of all, the needle can injure vessels. However, the damage is largely preventable by the routine use of ultrasound to ensure accurate real-time placement of the needle tip. The quality of real-time ultrasound guidance must be good, and the needle bevel must be seen at all times during needle advancement. It is also important to recognize that arterial puncture is reduced in frequency, but not entirely eliminated. There is no difference between out of plane and in plane technique.

Secondly, guidewires, if excessive force is used, can exit the veins to pass into the pleura, mediastinum, or other structures.

Thirdly, dilators and catheters passed along a guidewire will enlarge the tract diameter. If the guidewire is kinked or angulated, and further force was applied to the dilator ⁄ catheter, they can tear the vein wall and exit into adjacent tissues. Therefore, the guidewire should be repeatedly checked to ensure that it moves freely through the dilator ⁄ catheter, freely in the lumen of the vein and to ensure no distortion.

It is important to keep in mind that fluoroscopy or radiography can be falsely reassuring. There are cases where the catheter seems to be in the superior vena cava but is in an artery or the aorta.

 

Success rate depending on intervention

 

In 2017, Dixon (9) reviewed clinical cases reported in the literature and found 78 incidences of vascular injuries such as arterial cannulation. He compared the survival according to the management:

In the group removal and compress:17patients,many serious complications: 3 deaths; 5.6% success In the group interventional radiology: 35 patients, 2 serious complications; 94.6% success In the group surgery: 37 patients; 100% success

Photo 2: Dixon’s (2017) review of clinical cases in the literature

 

The decision tree for dealing with inadvertent arterial canulation during placement of a CVC has been described by Dixon (2007) and Guibert (2008):

  • Confirm the arterial lesion by the pulsatile flow (sometimes unrecognized), by the rapid extension of a hematoma, by the measurement of blood gases, by the taking of pressures, by the imaging with ultrasound, CT or MRI.
  • The patient should be regularly assessed, especially if there are airway disorders or neurological deficits.
  • If there is arterial damage from the needle or guidewire, and the vessel can be easily compressed, it can be removed and compressed for 15 minutes. If the vessel is not compressible, then endovascular or surgical repair is required.
  • When the arterial injury is discovered after the catheter or introducer has been placed, the hole is bigger, and a surgical or radiological opinion is required before removal.

Venous injuries also exist and can be very serious.

Collier published a six-year series of twenty one venous wounds; the operators (anesthetist, surgeon, radiologists) recall pushing the dilator completely. Sometimes, radiological documentation was available. Seventeen deaths were observed. The same decision tree should be used.

Conclusions - how to prevent acute vascular injuries during CICC placements. Prevention of these injuries is paramount. Use ultrasound in real time to puncture veins. Wires and dilators must never be advanced against any resistance. Guidewire should be repeatedly checked to ensure it moves freely throught the dilatator, to ensure no distortion. Dilators should only be advanced far enough to enter the vein that is accessed and no further. If a catheter is misplaced, it must not be removed until the operator is ready to take care of the hole in the vein or in the artery. Shorter dilators should be provided in the insertion kits so that they only are used to dilate the skin, subcutaneous tissue, muscle, and entry in to the vein. A decisional tree must be immediately available in your hospital, in your operating room.

Photo 3: Conclusions on how to prevent acute vascular injuries during CICC placements

 

Here is the decision tree that should be put in the rooms where central lines are placed:

 

Management suggestion and decisional tree for inadvertent arterial cannulation during CICC placements like central venous catheterisation

Photo 4: Decision tree for inadvertent arterial cannulation during CICC placements

 

Bibliography

 

– Domino KB, Bowdle TA, Posner KL, Spitellie PH, Lee LA, Cheney FW. Injuries and Liability Related to Central Vascular Catheters. Anesthesiology. 1 juin 2004;100(6):1411‑8.

– Adeogba. Central venous access complications Closed claim update. Closed Claim. (116):539‑73.

– Cook TM. Litigation related to central venous access by anaesthetists: an analysis of claims against the NHS in England 1995-2009: Correspondence. Anaesthesia. janv 2011;66(1):56‑7.

– Björkander M, Bentzer P, Schött U, Broman ME, Kander T. Mechanical complications of central venous catheter insertions: A retrospective multicenter study of incidence and risks. Acta Anaesthesiol Scand. janv 2019;63(1):61‑8.

– Thomas AN, MacDonald JJ. A review of patient safety incidents reported as ‘severe’ or ‘death’ from critical care units in England and Wales between 2004 and 2014. Anaesthesia. sept 2016;71(9):1013‑23.

– Lathey RK, Jackson RE, Bodenham A, Harper D, Patle V, the Anaesthetic Audit and Research Matrix of Yorkshire (AARMY). A multicentre snapshot study of the incidence of serious procedural complications secondary to central venous catheterisation. Anaesthesia. mars 2017;72(3):328‑34.

– Guilbert M-C, Elkouri S, Bracco D, Corriveau MM, Beaudoin N, Dubois MJ, et al. Arterial trauma during central venous catheter insertion: Case series, review and proposed algorithm. J Vasc Surg. oct 2008;48(4):918‑25.

– Bowdle A. Vascular Complications of Central Venous Catheter Placement: Evidence-Based Methods for Prevention and Treatment. J Cardiothorac Vasc Anesth. avr 2014;28(2):358‑68.

– Oliver G.B. Dixon, George E. Smith, Daniel Carradice, Ian C. Chetter. A systematic review of management of inadvertent arterial injury during central venous catheterisation. J Vasc Access 2017; 18 (2): 97-102 DOI: 10.5301/jva.5000611

– Collier PE. Prevention and treatment of dilator injuries during central venous catheter placement. J Vasc Surg Venous Lymphat Disord. nov 2019;7(6):789‑92.

 


 

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About the author

<a href="https://vascufirst.com/author/herve-rosay/" target="_self">Herve Rosay</a>

Herve Rosay

Hervé Rosay is an Anaesthesiologist Doctor who practiced in the AHBL Mont Saint Martin Hospital, then in the Leon Berard Center in Lyon as the Head of the Vascular Access Department, both in France. He is an expert in Vascular Access and was a member and speaker in the organization of the Vascular Access University Degree in Lyon and Paris. Dr Rosay was also the one who introduced advanced CVC placement practices for nurses in France.

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